Phenibut can be an analogue of GABA. The addition of the phenyl ring makes it possible for Phenibut to cross the blood-brain barrier far more very easily than GABA taken as a supplement.Phenibut is an analog of the brain chemical gamma-aminobutyric acid or GABA, the principal inhibitory neurotransmitter.The Pd-catalyzed intramolecular Heck response